Coupled experimental-modeling analyses of heat transfer in ex-vivo VS55-perfused porcine hepatic tissue being plunged in liquid nitrogen for vitreous cryopreservation

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• 作者：Zhendong Jiang^a ; ¹ ; Gang Zhao^a ; ^b ; ^{ZhaoG@ustc.edu.cn} ; S. M. Chapal Hossain^a ; ¹ ; Dayong Gao^c
• 关键词：Cryopreservation ; Thermal conductivity ; Vitrification ; Convective heat transfer coefficient ; VS55 ; Porcine liver
• 刊名：International Journal of Heat and Mass Transfer
• 出版年：2017
• 出版时间：March 2017
• 年：2017
• 卷：106
• 期：Complete
• 页码：970-979
• 全文大小：2925 K
• 卷排序：106

文摘

A coupled experimental-modeling analyses of heat transfer in large scale biomaterials during vitrification cryopreservation was successfully developed. Thermal conductivities of VS55 and the VS55-perfused porcine hepatic tissue at −196 to 37 °C were measured. The convective heat transfer coefficients on the outer surface of a cryovial plunged into liquid nitrogen were determined with an inverse problem method. The heat transfer in ex-vivo VS55-perfused porcine hepatic tissue being plunged in LN​2​ for vitreous cryopreservation was precisely modelled.