Berberine alleviates postoperative cognitive dysfunction by suppressing neuroinflammation in aged mice
详细信息 查看全文
- 作者：Zhijie Zhanga ; Xiuhua Lib ; Fayin Lia ; Lijun Ana ; lijunan2000@126.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：Postoperative cognitive dysfunction ; Berberine ; Aged ; Microglia ; Inflammation
- 刊名：International Immunopharmacology
- 出版年：2016
- 出版时间：September 2016
- 年：2016
- 卷：38
- 期：Complete
- 页码：426-433
- 全文大小：2210 K
文摘
- •
Postoperative cognitive dysfunction (POCD) is a common complication after surgery.
- •
Neuroinflammation has played a key role in the pathophysiology of POCD.
- •
Berberine possesses anti-inflammatory and anti-oxidant effects.
- •
Berberine rescued surgery-induced cognitive and the related brain impairment.