Electrophysiological assessment of Guillain-Barré syndrome with both Gal-C and ganglioside antibodies; tendency for demyelinating type

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• 作者：Makoto Samukawa ; MD ; PhD^a ; Motoi Kuwahara ; MD ; PhD^a ; Miyuki Morikawa ; MD^a ; Rino Ueno ; MD ; PhD^a ; Yukihiro Hamada ; MD ; PhD^a ; Kazuo Takada ; MD ; PhD^a ; Makito Hirano ; MD ; PhD^a ; ^b ; Yoshiyuki Mitsui ; MD ; PhD^a ; Masahiro Sonoo ; MD ; PhD^c ; Susumu Kusunoki ; MD ; PhD^a ; ^{kusunoki-tky@umin.ac.jp}
• 关键词：GBS ; Guillain&ndash ; Barré ; syndrome ; Gal-C ; galactocerebroside ; Gal-C-GS-GBS ; GBS with antibodies to Gal-C and gangliosides ; ELISA ; enzyme-linked immunosorbent assay ; NCS ; nerve conduction studies ; CMAP ; Compound muscle action potential ; MDL ; motor nerve distal latency ; MCV ; motor nerve conduction velocity ; SCV ; sensory nerve conduction velocity ; SNAP ; sensory nerve action potential ; AIDP ; acute inflammatory demyelinating polyneuropathy ; AMAN ; acute motor axonal neuropathy
• 刊名：Journal of Neuroimmunology
• 出版年：2016
• 出版时间：15 December 2016
• 年：2016
• 卷：301
• 期：Complete
• 页码：61-64
• 全文大小：182 K
• 卷排序：301

文摘

GBS patients with antibodies to Gal-C tend to have demyelinating neuropathy. Subtype of GBS with both Gal-C and ganglioside antibodies remains controversial. Eight of 16 GBS cases with both antibodies (Gal-C-GS-GBS) were demyelinating type. None of the patients with Gal-C-GS-GBS exhibited axonal neuropathy. Coexistence of Gal-C and ganglioside antibodies may be associated with demyelination.