A tethered aminohydroxylation route to l
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- 作者：Abhishek Dubey ; Pradeep Kumar
- 关键词：Sharpless asymmetric kinetic resolution ; Tethered aminohydroxylation ; Regioselectivity ; Stereoselectivity ; Phytosphingosine ; Sphingolipids
- 刊名：Tetrahedron Letters
- 出版年：2009
- 出版时间：1 July 2009
- 年：2009
- 卷：50
- 期：26
- 页码：3425-3427
- 全文大小：236 K
文摘
A concise and highly efficient synthesis of l-arabino-[2R,3S,4R] and l-xylo-[2R,3S,4S]-C18-phytosphingosines has been achieved. The synthetic strategy features the Sharpless kinetic resolution and tethered aminohydroxylation as the key steps.