Individual and combined in vitro (anti)androgenic effects of certain food additives and cosmetic preservatives
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- 作者：Anca Popa ; anca.pop@umfcluj.ro" class="auth_mail" title="E-mail the corresponding author ; Tudor Druganb ; tdrugan@umfcluj.ro" class="auth_mail" title="E-mail the corresponding author ; Arno C. Gutlebc ; arno.gutleb@list.lu" class="auth_mail" title="E-mail the corresponding author ; Diana Lupua ; lupu.diana@umfcluj.ro" class="auth_mail" title="E-mail the corresponding author ; Julien Cherfana ; cherfanjul@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Felicia Loghina ; floghin@umfcluj.ro" class="auth_mail" title="E-mail the corresponding author ; Bé ; la Kissa ; kbela@umfcluj.ro" class="auth_mail" title="E-mail the corresponding author
- 关键词：Endocrine disruptor ; Anti-androgen ; In vitro ; Mixture ; Luciferase
- 刊名：Toxicology in Vitro
- 出版年：2016
- 出版时间：April 2016
- 年：2016
- 卷：32
- 期：Complete
- 页码：269-277
- 全文大小：819 K
文摘
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Certain food additives & cosmetic preservatives are potential endocrine disruptors.
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The selected compounds had no in vitro androgenic activity.
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Three of the selected compounds showed in vitro anti-androgenic activity.
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The effect of binary mixtures could be predicted by the dose addition model.