BBD was employed to extract bioactive compounds from GBP using PHWE.
The best extraction parameters were 207 °C, 43.45 bar, 0.04 g/mL, 199 RPM and 15 min.
The experimental extraction curves were fitted with the steady-state kinetic model.
Homogentisic acid and gentisic acid were the main phenolic compounds obtained.
The optimized condition showed good antimicrobial and antihypertensive activities.