Addendum guidelines for the prevention of peanut allergy in the United States: Report of the National Institute of Allergy and Infectious Diseases-sponsored expert panel

详细信息    查看全文

• 作者：Alkis Togias ; MD^a ; Susan F. Cooper ; MSc^a ; ^{coopersu@niaid.nih.gov} ; Maria L. Acebal ; JD^b ; Amal Assa'ad ; MD^c ; James R. Baker Jr. ; MD^d ; Lisa A. Beck ; MD^e ; Julie Block^f ; Carol Byrd-Bredbenner ; PhD ; RD ; FAND^g ; Edmond S. Chan ; MD ; FRCPC^h ; Lawrence F. Eichenfield ; MDⁱ ; David M. Fleischer ; MD^j ; George J. Fuchs III ; MD^k ; Glenn T. Furuta ; MD^l ; Matthew J. Greenhawt ; MD ; MBA ; MSc^j ; Ruchi S. Gupta ; MD ; MPH^m ; Michele Habich ; DNP ; APN/CNS ; CPNⁿ ; Stacie M. Jones ; MD^o ; Kari Keaton^p ; Antonella Muraro ; MD ; PhD^q ; Marshall Plaut ; MD^a ; Lanny J. Rosenwasser ; MD^r ; Daniel Rotrosen ; MD^a ; Hugh A. Sampson ; MD^s ; Lynda C. Schneider ; MD^t ; Scott H. Sicherer ; MD^u ; Robert Sidbury ; MD ; MPH^v ; Jonathan Spergel ; MD ; PhD^w ; David R. Stukus ; MD^x ; Carina Venter ; PhD ; RD^y ; Joshua A. Boyce ; MD^z
• 关键词：Food ; peanut ; allergy ; prevention ; guidelines
• 刊名：Journal of Allergy and Clinical Immunology
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：139
• 期：1
• 页码：29-44
• 全文大小：371 K
• 卷排序：139

文摘

Food allergy is an important public health problem because it affects children and adults, can be severe and even life-threatening, and may be increasing in prevalence. Beginning in 2008, the National Institute of Allergy and Infectious Diseases, working with other organizations and advocacy groups, led the development of the first clinical guidelines for the diagnosis and management of food allergy. A recent landmark clinical trial and other emerging data suggest that peanut allergy can be prevented through introduction of peanut-containing foods beginning in infancy.ObjectivesPrompted by these findings, along with 25 professional organizations, federal agencies, and patient advocacy groups, the National Institute of Allergy and Infectious Diseases facilitated development of addendum guidelines to specifically address the prevention of peanut allergy.ResultsThe addendum provides 3 separate guidelines for infants at various risk levels for the development of peanut allergy and is intended for use by a wide variety of health care providers. Topics addressed include the definition of risk categories, appropriate use of testing (specific IgE measurement, skin prick tests, and oral food challenges), and the timing and approaches for introduction of peanut-containing foods in the health care provider's office or at home. The addendum guidelines provide the background, rationale, and strength of evidence for each recommendation.ConclusionsGuidelines have been developed for early introduction of peanut-containing foods into the diets of infants at various risk levels for peanut allergy.