The use of abrasive polishing and laser processing for developing polyurethane surfaces for controlling fibroblast cell behaviour

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• 作者：Michael Irving^a ; Mark F Murphy^a ; ; Francis Lilley^a ; Paul W French^a ; David R Burton^a ; Simon Dixon^b ; Martin C Sharp^a
• 关键词：Laser processing ; Abrasive polishing ; Cell adhesion ; Cell proliferation ; Cell migration
• 刊名：Materials Science and Engineering: C
• 出版年：2017
• 出版时间：1 February 2017
• 年：2017
• 卷：71
• 期：Complete
• 页码：690-697
• 全文大小：1083 K
• 卷排序：71

文摘

Abrasive polishing can generate nano-scratches on stainless steel to cast polymer films for cell substrates/coatings. Introducing fibroblast cells to the polymer surface having randomly organised features enhanced cell adhesion/proliferation. Surfaces generated using laser processing enhanced cell adhesion/proliferation similarly to the randomly polished surface. Cells growing on the surface having directional nano-features did not enhance cell adhesion or cell migration. The work offers potential to develop nano-textured coatings using abrasive polishing methods for biomedical implants.