Insights on methotrexate in psoriatic disease
详细信息 查看全文
- 作者：Jacqueline E. Greba ; b ; jegreb@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Ari M. Goldminza ; b ; ari.goldminz@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Alice B. Gottliebb ; alice.gottlieb@gmail.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：PASI ; psoriasis area and severity index ; AICAR ; 5-aminoimidazole-4-carboxamide ribonucleotide ; APCP ; α ; β-methylene adenosine-5&prime ; -diphosphate ; IL ; interleukin ; CVD ; cardiovascular disease ; DC ; dendritic cell
- 刊名：Clinical Immunology
- 出版年：2016
- 出版时间：November 2016
- 年：2016
- 卷：172
- 期：Complete
- 页码：61-64
- 全文大小：244 K
文摘
- •
Methotrexate is an anti-inflammatory agent used to treat psoriasis, psoriatic arthritis, and other immune mediated disorders.
- •
Adenosine signaling plays a key role in methotrexate's anti-inflammatory properties through modulation of T-cell activity.
- •
Future applications of methotrexate may include cardiovascular disease risk modification in susceptible patient populations.
© 2004-2018 中国地质图书馆版权所有 京ICP备05064691号 京公网安备11010802017129号 地址：北京市海淀区学院路29号 邮编：100083 电话：办公室：(+86 10)66554848；文献借阅、咨询服务、科技查新：66554700 |