A case of tophaceous pseudogout of the temporomandibular joint extending to the base of the skull

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• 作者：K. Kudoh¹ ; ^{kkudoh@tokushima-u.ac.jp} ; T. Kudoh¹ ; K. Tsuru² ; Y. Miyamoto¹
• 关键词：calcium pyrophosphate dihydrate ; Fourier transform infrared spectroscopy ; temporomandibular joint ; tophaceous pseudogout ; X-ray diffraction
• 刊名：International Journal of Oral and Maxillofacial Surgery
• 出版年：2017
• 出版时间：March 2017
• 年：2017
• 卷：46
• 期：3
• 页码：355-359
• 全文大小：994 K
• 卷排序：46

文摘

A case of tophaceous pseudogout (i.e., calcium pyrophosphate dihydrate (CPPD) crystal deposition disease) in the temporomandibular joint (TMJ), extending to the base of the skull, is reported. A 38-year-old man was referred to the hospital with mild pain in the right chin and tip of the tongue. Panoramic radiography showed a large calcified mass around the right TMJ. Computed tomography imaging revealed a large, granular, calcified mass surrounding the right condylar head and extending to the base of the skull. The mass was clinically and radiographically suspected to be a pseudogout lesion. A biopsy specimen was collected under general anaesthesia to confirm the diagnosis. On histology, the mass was found to contain deposits of numerous rod-shaped and rhomboid crystals, which suggested tophaceous pseudogout. The deposits were identified as CPPD crystal deposition, based on analysis by X-ray diffraction and Fourier transform infrared spectroscopy. These two crystallography methods were useful in confirming the diagnosis of CPPD crystal deposition disease in the TMJ.