Simultaneous determination of polycyclic aromatic hydrocarbons and tobacco-specific N-nitrosamines in mainstream cigarette smoke using in-pipette-tip solid-phase extraction and on-line gel permeation chromatography-gas chromatography-tandem mass spectrometry
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- 作者：Yan-Bo Luo ; Xiao-Jing Chen ; Hong-Fei Zhang ; Xing-Yi Jiang ; Xue Li ; Xiang-Yu Li ; Feng-Peng Zhu ; Yong-Qiang Pang ; 36140501@qq.com" class="auth_mail" title="E-mail the corresponding author ; Hong-Wei Hou
- 关键词：Silica/primary secondary amine (SiO2/PSA) ; In-pipette-tip solid phase extraction (SPE) ; Polycyclic aromatic hydrocarbons (PAHs) ; Tobacco-specific N-nitrosamines (TSNAs) ; On-line gel permeation chromatography-gas chromatography/tandem mass spectrometry (on-line GPC-GC&ndash ; MS2)
- 刊名：Journal of Chromatography A
- 出版年：2016
- 出版时间：19 August 2016
- 年：2016
- 卷：1460
- 期：Complete
- 页码：16-23
- 全文大小：1495 K
文摘
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In-pipette-tip SPE was applied for purification of mainstream smoke (MSS) extract.
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The sample preparation process can be accomplished within a very short time.
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A method for simultaneous determination of PAHs and TSNAs in MSS was established.
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The method has the advantages of simplicity, rapidity and high-efficiency.