A novel fluorogenic probe for monoamine oxidase assays

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• 作者：You You Lu ; Yu Guang Wang ; Bin Dai ; Yi Qi Dai ; Zhao Wang ; Zheng Wei Fu ; Qing Zhu
• 关键词：Monoamine oxidase ; Fluorogenic probe ; Assay
• 刊名：Chinese Chemical Letters
• 出版年：2008
• 出版时间：August 2008
• 年：2008
• 卷：19
• 期：8
• 页码：947-950
• 全文大小：303 K

文摘

Monoamine oxidase is flavoenzymes, widely distributed in mammals. It is well recognized that MAOs serve an important role in metabolism that they have close relationship with health .Along with the discoveries between MAOs and neurotic disease, more and more studies have been jumped in .In this paper, we design a new probe for assaying the activities of MAOs. The results showed that the probe [7-(3-aminopropoxy)coumarin] is simple, effective and sensitive for MAOB.