Vitrification transiently alters Oct-4, Bcl2 and P53 expression in mouse morulae but does not affect embryo development in vitro
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- 作者：Guangbin Zhoua ; 1 ; zguangbin@sicau.edu.cn" class="auth_mail" title="E-mail the corresponding author ; Yan Zengb ; c ; 1 ; Jiang Guoa ; Qinggang Mengd ; Qingyong Menge ; Gongxue Jiaf ; Keren Chengb ; Changjun Zenga ; Ming Zhanga ; Guoshi Liub ; Shi'en Zhub
- 关键词：Vitrification ; Mouse morulae ; Oct-4 ; Apoptosis genes ; Blastocyst rate
- 刊名：Cryobiology
- 出版年：2016
- 出版时间：October 2016
- 年：2016
- 卷：73
- 期：2
- 页码：120-125
- 全文大小：822 K
文摘
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Mouse morula were cryopreserved by open-pulled straw (OPS) method.
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OPS vitrification caused alteration of mRNA expression of genes (Oct-4, bcl2 and p53).
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The changed genes expression showed no negative impact on the in vitro development of morula.
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