Recognition of alternatively spliced cassette exons based on a hybrid model
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- 作者：Xiaokang Zhang ; Qinke Peng ; qkpeng@mail.xjtu.edu.cn" class="auth_mail" title="E-mail the corresponding author ; Liang Li ; Xintong Li
- 关键词：Cassette exons ; Constitutive exons ; Hybrid model ; Gene expression programming ; Random forests
- 刊名：Biochemical and Biophysical Research Communications
- 出版年：2016
- 出版时间：11 March 2016
- 年：2016
- 卷：471
- 期：3
- 页码：368-372
- 全文大小：414 K
文摘
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An effective hybrid method is proposed for recognition of alternatively spliced cassette exons.
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Cassette exons can be distinguished from constitutive exons with high accuracy.
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Conservation based features are proven to be very important in predicting splicing behavior.