Synthesis, spectroscopic properties and photodynamic activity of two cationic BODIPY derivatives with application in the photoinactivation of microorganisms

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• 作者：Maximiliano L. Agazzi¹ ; M. Belé ; n Ballatore¹ ; Eugenia Reynoso ; Ezequiel D. Quiroga ; Edgardo N. Durantini ; ^{edurantini@exa.unrc.edu.ar}
• 关键词：BODIPY ; Photosensitizer ; Photooxidation ; Singlet oxygen ; Potassium iodide ; Photodynamic inactivation
• 刊名：European Journal of Medicinal Chemistry
• 出版年：2017
• 出版时间：27 January 2017
• 年：2017
• 卷：126
• 期：Complete
• 页码：110-121
• 全文大小：974 K
• 卷排序：126

文摘

Cationic BODIPYs derivatives were synthesized as photodynamic agents. BODIPYs show low singlet molecular oxygen production. A contribution of type I photoprocess was involved in the decomposition of l-tryptophan. The addition of KI produced an increase in the photoinduced decomposition of Trp.