A splicing isoform of Ctenopharyngodon idella ADAR1 (CiADAR1-like): Genome organization, tissue specific expression and transcriptional regulation
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- 作者：Binhua Wang ; Yong Liu ; Zhicheng Sun ; Xiancheng Liu ; Yichuan Mi ; Dan Liu ; Xiaowen Xu ; Qunhao Hou ; Fang Wang ; Chengyu Hu ; hucy2008@163.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：ADAR1-like ; IRF1 and IRF3 ; Transcriptional regulation ; Splicing isoform ; Teleost fish
- 刊名：Fish & Shellfish Immunology
- 出版年：2015
- 出版时间：November 2015
- 年：2015
- 卷：47
- 期：1
- 页码：535-544
- 全文大小：2475 K
文摘
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A splicing isoform of Ctenopharyngodon idella ADAR1 was cloned and identified.
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CiADAR1-like genome has 9 exons and 8 introns.
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CiADAR1-like promoter region contains 3 ISRE and 8 IRF-E.
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CiADAR1-like was significantly up-regulated after stimulation with poly I:C.
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Both IRF1 and IRF3 could activate the transcription of CiADAR1-like.
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