LDL cholesterol in early pregnancy and offspring cardiovascular disease risk factors

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• 作者：Jacob J. Christensen ; MSc^a ; ^b ; Kjetil Retterstø ; l ; MD ; PhD^a ; ^b ; Kristin Godang ; BSc^c ; ^d ; Marie Cecilie Paasche Roland ; MD ; PhD^d ; ^e ; Elisabeth Qvigstad ; MD ; PhD^c ; Jens Bollerslev ; MD ; PhD^c ; ^d ; Thor Ueland ; PhD^d ; ^f ; Tore Henriksen ; MD ; PhD^d ; ^e ; Kirsten B. Holven ; PhD^a ; ^g ; ^{k.b.holven@medisin.uio.no}
• 关键词：Hypercholesterolemia ; Pregnancy ; Risk factors ; Children ; LDL
• 刊名：Journal of Clinical Lipidology
• 出版年：2016
• 出版时间：November-December 2016
• 年：2016
• 卷：10
• 期：6
• 页码：1369-1378.e7
• 全文大小：484 K
• 卷排序：10

文摘

Studies on relation between maternal LDL-C in pregnancy and offspring risk are scarce. We measured CVD risk in offspring of women with high or low LDL-C in pregnancy. LDL-C was higher in 6-to-13-year-old offspring whose mothers had high LDL-C. The difference in offspring cholesterol is clinically relevant. Promoting a healthy lifestyle among young women may be particularly beneficial.