Rabies virus phosphoprotein interacts with ribosomal protein L9 and affects rabies virus replication
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- 作者：Youwen Lia ; b ; d ; 1 ; Wanyu Donga ; b ; 1 ; Yuejun Shia ; b ; Feng Denga ; b ; Xi Chena ; b ; Chunyun Wanb ; Ming Zhoua ; b ; Ling Zhaoa ; b ; Zhen F. Fua ; b ; c ; zhenfu@uga.edu" class="auth_mail" title="E-mail the corresponding author ; Guiqing Penga ; b ; penggq@mail.hzau.edu.cn" class="auth_mail" title="E-mail the corresponding author
- 关键词：Rabies virus ; Ribosomal protein L9 ; Protein interaction ; Viral replication and transcription
- 刊名：Virology
- 出版年：2016
- 出版时间：15 January 2016
- 年：2016
- 卷：488
- 期：Complete
- 页码：216-224
- 全文大小：4868 K
文摘
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RABV phosphoprotein (P) binds to L9 both in vitro and in vivo.
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The central domain of P and the C terminus of L9 is essential for its interaction.
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P stimulates the translocation of L9 from the nucleus to the cytoplasm.
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Overexpression or knockdown of L9 affect RABV replication.