Anticonvulsant properties of Euterpe oleracea in mice
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- 作者：José ; Rogerio Souza-Monteiroa ; Moisé ; s Hamoyb ; Danielle Santana-Coelhoa ; Gabriela P.F. Arrifanoa ; Ricardo S.O. Paraensea ; Allan Costa-Malaquiasa ; Jackson R. Mendonç ; aa ; Rafael F. da Silvac ; Wallena S.C. Monteiroc ; Hervé ; Rogezd ; Diogo L. de Oliveirae ; José ; Luiz M. do Nascimentof ; Maria Elena Crespo-Ló ; peza ; maria.elena.crespo.lopez@gmail.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：Seizure ; Euterpe oleracea ; Anticonvulsant ; Oxidative stress ; EEG ; Amazon
- 刊名：Neurochemistry International
- 出版年：2015
- 出版时间：November 2015
- 年：2015
- 卷：90
- 期：Complete
- 页码：20-27
- 全文大小：2071 K
文摘
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Clarified açai (Euterpe oleracea Mart.) juice (EO) did not affect locomotor activity.
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Four doses of EO were sufficient to improve behavioral alterations caused by seizures.
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EO decreased amplitude of discharges and frequencies >50 Hz in electrocorticograms.
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EO reduced lipid peroxidation caused by seizures in the cerebral cortex of mice.
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EO showed a potent direct scavenging property, higher than that of ascorbic acid.