O3 initial concentration is the most critical parameter for ranitidine removal.
Alkaline pH of the solution promotes removal and overall mineralization.
11 TPs of ranitidine were detected and structurally elucidated by LC-Q-ToF-MS.
Both HILIC and RPLC were used as a holistic approach for TPs identification.
Retention time prediction was used as a supporting tool for TPs identification.