The association of IL-18 gene promoter polymorphisms and the levels of serum IL-18 on the risk of multiple sclerosis
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- 作者：Gü ; rdal Orhana ; Esra Eruyara ; Semra Ö ; ztü ; rk Mungana ; Fikri Aka ; Bensu Karahalilb ; bensuka@gmail.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：Multiple sclerosis ; IL-18 gene polymorphism ; PCR ; IL-18 activity
- 刊名：Clinical Neurology and Neurosurgery
- 出版年：2016
- 出版时间：July 2016
- 年：2016
- 卷：146
- 期：Complete
- 页码：96-101
- 全文大小：720 K
文摘
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IL-18 −607AA genotype indicated 6 times higher risk in the development of disease.
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Smoking is a confounding factor in patients with IL-18 −607CA + AA genotypes.
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No meaningful association was found with IL-18 −137C/G gene promoter polymorphism.