Sugar-based novel chiral macrocycles for inclusion applications and chiral recognition
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- 作者：Ankita Singh ; Vinod Khatri ; Shashwat Malhotra ; Ashok K. Prasad ; ashokenzyme@gmail.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：Macrocycle ; Click reaction ; Template assisted ; Benzyl ammonium perchlorate ; Phenylalanine ; Chiral recognition
- 刊名：Carbohydrate Research
- 出版年：2016
- 出版时间：8 February 2016
- 年：2016
- 卷：421
- 期：Complete
- 页码：25-32
- 全文大小：2085 K
文摘
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A convergent template assisted synthesis of sugar-based chiral macrocycles has been described.
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The host–guest inclusion studies have revealed selective interactions of the synthesized macrocycle with the primary instead of secondary ammonium salt.
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The synthesized chiral macrocycle also discriminates between D- and L-phenylalanine methyl ester salts as revealed by 1H NMR spectral studies of the host-guest mixture.