Critical review of statins: A bio-analytical perspective for therapeutic drug monitoring

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• 作者：Misari Patel ; Charmy Kothari ; ^{charmyshah@gmail.com}
• 关键词：Bio-analytical techniques ; Statins ; HMG-CoA reductase inhibitors ; Review ; Sample extraction ; Biological fluids ; Therapeutic drug monitoring
• 刊名：TrAC Trends in Analytical Chemistry
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：86
• 期：Complete
• 页码：206-221
• 全文大小：545 K
• 卷排序：86

文摘

Bio-analytical techniques for quantitation of statins and their metabolites in biological fluids is discussed. A concise tabular summary of each bio-analytical technique with respect to method and its nuances also presented. Most methods summarized allow quantitation of statins in the ng/ml range.