Interferon lambda and hepatitis C virus core protein polymorphisms associated with liver cancer
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- 作者：Joã ; o Paulo Moreiraa ; b ; Fernanda de Mello Maltaa ; b ; femalta@yahoo.com" class="auth_mail" title="E-mail the corresponding author ; Má ; rcio Augusto Dinizb ; c ; Luciana Kikuchib ; Aline Lopes Chagasb ; Livia de Souza Botelho Limaa ; b ; Michele Soares Gomes-Gouvê ; aa ; b ; Vanessa Fusco Duarte de Castrod ; Rubia Anita Ferraz Santanad ; Nairo Massakazu Sumitae ; Denise Cerqueira Paranagua Vezozzob ; Flair José ; Carrilhob ; Joã ; o Renato Rebello Pinhoa ; b ; d
- 关键词：Hepatitis C virus ; Chronic hepatitis ; Mutation ; Infection ; Oncogenesis ; Immune responses
- 刊名：Virology
- 出版年：2016
- 出版时间：June 2016
- 年：2016
- 卷：493
- 期：Complete
- 页码：136-141
- 全文大小：393 K
文摘
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We found association between the rs12980275-AG and hepatocellular carcinoma.
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HCV core substitutions R70Q and L91M were more frequente in genotype 1b.
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R70Q substitution may be associated with the rs12980275-AG.