Candida parapsilosis: A versatile biocatalyst for organic oxidation-reduction reactions
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- 作者：Anju Chadhaa ; b ; anjuc@iitm.ac.in" class="auth_mail" title="E-mail the corresponding author ; Sowmyalakshmi Venkataramana ; 1 ; Radhakrishnan Preethaa ; 2 ; Santosh Kumar Padhic
- 关键词：Candida sp. ; Candida species ; C. parapsilosis ; Candida parapsilosis ; FDH ; formate dehydrogenase ; PDH ; phenylalanine dehydrogenase ; ACE ; angiotensin-converting enzyme ; NEP ; neutral endopeptidase ; KR ; kinetic resolution ; BDO ; 1 ; 3-butanediol ; PED ; 1-phenyl-12-ethanediol ; CpSADH ; secondary alcohol dehydrogenase from C. parapsilosis ; ee ; enantiomeric excess ; CpCR ; carbonyl reductase from C. parapsilosis ; AKR ; aldo-keto reductase ; CPR ; conjugated polyketone reductases ; CprCR ; (R)-specific carbonyl red
- 刊名：Bioorganic Chemistry
- 出版年：2016
- 出版时间：October 2016
- 年：2016
- 卷：68
- 期：Complete
- 页码：187-213
- 全文大小：7669 K
文摘
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C. parapsilosis catalyzes:
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the asymmetric reduction of carbonyl compounds and imines.
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deracemization reactions to prepare optically pure secondary alcohols.
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oxidative kinetic resolution and oxidation reactions.
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The mechanism of redox reactions are understood using purified enzymes of this yeast.