Negative mood-induction modulates default mode network resting-state functional connectivity in chronic depression

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• 作者：Fritz Renner^a ; ^b ; ¹ ; ^{Fritz.Renner@mrc-cbu.cam.ac.uk} ; Nicolette Siep^b ; Arnoud Arntz^c ; Vincent van de Ven^d ; Frenk P.M.L. Peeters^e ; Conny W.E.M. Quaedflieg^b ; ^f ; Marcus J.H. Huibers^g
• 关键词：Mood-induction ; Chronic depression ; Resting state fMRI ; Default mode network ; Posterior cingulate cortex
• 刊名：Journal of Affective Disorders
• 出版年：2017
• 出版时间：15 January 2017
• 年：2017
• 卷：208
• 期：Complete
• 页码：590-596
• 全文大小：481 K
• 卷排序：208

文摘

We studied effects of mood on default mode network connectivity in chronic depression. Resting state fMRI was performed before and after a sad mood-induction. Default mode network connectivity was modulated by induced mood-states. Connectivity generally increased in patients vs controls after the mood induction.