Homoiterons and expansion in ribosomal RNAs
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- 作者：Michael S. Parkerc ; Floyd R. Salleeb ; Edwards A. Parka ; Steven L. Parkera ; stevenleonardparker@msn.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：aa ; amino acid residues ; ES ; an expansion segment ; LSU ; large cytoplasmic ribosome subunit (50S in prokaryotes and archaea ; 60S in eukaryotes) ; mRNP ; messenger ribonucleoprotein ; ncRNA ; non-coding RNA ; nt ; nucleotides ; PCN ; homoionic motifs with ⩾3% and ⩾50% ionic residues ; found especially in Polynucleotide-binding proteins ; Carrier proteins and Nuclear localization signals ; SSU ; small cytoplasmic ribosome subunit (30S in prokaryotes and archaea ; 40S in eukaryotes) ; u ; nucleotide unit ; XN or NX
- 刊名：FEBS Open Bio
- 出版年：2015
- 出版时间：2015
- 年：2015
- 卷：5
- 期：Complete
- 页码：864-876
- 全文大小：2464 K
文摘
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Homoiterons like GGGGGGG stabilize ribosomal RNAs of thermophile prokaryotes.
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In eukaryotes, homoiterons are much more abundant in RNA of the larger subunit (LSU).
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The LSU repeats increase with phylogenetic rank to 28% entire RNA sequence in hominids.
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In mammal LSU RNAs, these repeats constitute 45% of the massive expansion segments.
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These repeats may help in anchoring of ribosomes and export of secretory proteins.