Metabolic phenotype of bladder cancer
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- 作者：Francesco Massaria ; 1 ; fmassari79@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Chiara Ciccareseb ; 1 ; Matteo Santonic ; Roberto Iacovellib ; Roberta Mazzucchellid ; Francesco Pivae ; Marina Scarpellid ; Rossana Berardic ; Giampaolo Tortorab ; Antonio Lopez-Beltranf ; Liang Chengg ; Rodolfo Montironid ; 2 ; r.montironi@univpm.it" class="auth_mail" title="E-mail the corresponding author
- 关键词：Bladder cancer ; Metabolism ; Metabolic pathway ; Novel target
- 刊名：Cancer Treatment Reviews
- 出版年：2016
- 出版时间：April 2016
- 年：2016
- 卷：45
- 期：Complete
- 页码：46-57
- 全文大小：1220 K
文摘
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Metabolism of bladder cancer represents a key issue for cancer research.
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Bladder cancer metabolism displays an increased expression of genes contributing to cancer metabolic switch and tumor cell proliferation.
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Glycogen metabolism pathway plays a robust role in bladder cancer development.
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In this review we discuss the role of cancer metabolism in bladder cancer and the possible role for novel opportunities for targeted therapeutic strategies.