Impact of pneumococcal vaccination in children on serotype distribution in adult community-acquired pneumonia using the serotype-specific multiplex urinary antigen detection assay
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- 作者：Mathias W. Pletza ; b ; mathias.pletz@med.uni-jena.de" class="auth_mail" title="E-mail the corresponding author ; Santiago Ewigb ; c ; s.ewig@evk-herne.de" class="auth_mail" title="E-mail the corresponding author ; Gernot Rohdeb ; d ; e ; g.rohde@mumc.nl" class="auth_mail" title="E-mail the corresponding author ; Hartwig Schuetteb ; f ; hartwig.schuette@charite.de" class="auth_mail" title="E-mail the corresponding author ; Jan Ruppb ; g ; jan.rupp@uksh.de" class="auth_mail" title="E-mail the corresponding author ; Tobias Welteb ; e ; h ; welte.tobias@mh-hannover.de" class="auth_mail" title="E-mail the corresponding author ; Norbert Suttorpb ; f ; norbert.suttorp@charite.de" class="auth_mail" title="E-mail the corresponding author ; Christina Forstnera ; i ; christina.forstner@med.uni-jena.de" class="auth_mail" title="E-mail the corresponding author ; christina.a.forstner@meduniwien.ac.at" class="auth_mail" title="E-mail the corresponding author ; CAPNETZ Study Group
- 关键词：Pneumococcal vaccination ; Conjugate vaccines ; Pneumococcal pneumonia
- 刊名：Vaccine
- 出版年：2016
- 出版时间：29 April 2016
- 年：2016
- 卷：34
- 期：20
- 页码：2342-2348
- 全文大小：713 K
文摘
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SSUA was highly specific for all vaccine serotypes and highly sensitive for all blood isolates to detect pneumococcal pneumonia.
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PCV children vaccination program led to elimination of PCV7 serotypes in adult bacteremic pneumonia.
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A significant but not complete decrease in PCV7 serotypes was seen in non-bacteremic pneumonia.