Arachidonic acid metabolomic study of BPH in rats and the interventional effects of Zishen pill, a traditional Chinese medicine
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- 作者：Qiaoxia Bian ; Weihui Wang ; Nannan Wang ; Yan Peng ; Wen Ma ; Ronghua Dai ; ronghuadai@sina.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：Arachidonic acid ; Eicosanoids ; Biomarkers ; UHPLC&ndash ; MS/MS ; Benign prostatic hyperplasia ; Zishen pill
- 刊名：Journal of Pharmaceutical and Biomedical Analysis
- 出版年：2016
- 出版时间：5 September 2016
- 年：2016
- 卷：128
- 期：Complete
- 页码：149-157
- 全文大小：1621 K
文摘
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Developing the simultaneous determination method of arachidonic acid metabolome in biofluids.
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Evaluating the relationship between benign prostatic hyperplasia and AA metabolome.
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Study of metabonomics changes after administrated with Zishen pill.
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Presenting the interventional effects of drug through COX and LOX pathways of AA metabolism.
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