Enantioselective bis-alkoxycarbonylation of styrene catalyzed by novel chiral dipyridylphosphine cationic palladium(II) complexes

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• 作者：Wang ; Lailai ; Kwok ; Waihim ; Wu ; Jing ; Guo ; Rongwei ; Au-Yeung ; Terry T.-L. ; Zhou ; Zhongyuan ; Chan ; Albert S.C. ; et. al.
• 关键词：Asymmetric bis-alkoxycarbonylation ; Chiral diphosphines ; P-Phos ; Palladium complexes
• 刊名：Journal of Molecular Catalysis A: Chemical
• 出版年：2003
• 出版时间：April 1, 2003
• 年：2003
• 卷：196
• 期：1-2
• 页码：171-178
• 全文大小：141 K

文摘

The preparation of new palladium complexes that are composed of a series of chiral dipyridylphosphines [(R)-P-Phos (1), (R)-tol-P-Phos (2) and (R)-Xyl-P-Phos) (3)] have been described. The structure of the complex [{(R)-1}Pd(H₂O)₂](OTf)₂ was unambiguously determined by single-crystal X-ray diffractometry. These complexes were found to be effective in the asymmetric bis-methoxycarbonylation of styrene, reaching up to 84 % e.e. and 79 % chemoselectivity for dimethyl-2-phenylsuccinate (DMPS) under the optimal conditions. In addition, the complexes exhibited almost identical enantioselectivity on DMPS.