Acute Perinatal Sentinel Events, Neonatal Brain Injury Pattern, and Outcome of Infants Undergoing a Trial of Hypothermia for Neonatal Hypoxic-Ischemic Encephalopathy

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• 作者：Seetha Shankaran ; MD¹ ; ; Abbot R. Laptook ; MD² ; Scott A. McDonald ; BS³ ; Susan R. Hintz ; MD⁴ ; Patrick D. Barnes ; MD⁵ ; Abhik Das ; PhD³ ; Rosemary D. Higgins ; MD⁶ ; on behalf of Eunice Kennedy Shriver National Institute of Child Health ; Human Development Neonatal Research Network^*
• 关键词：intrapartum event ; magnetic resonance imaging ; neurodevelopment
• 刊名：The Journal of Pediatrics
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：180
• 期：Complete
• 页码：275-278.e2
• 全文大小：181 K
• 卷排序：180

文摘

Infants with perinatal sentinel events in the Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network Hypothermia for Encephalopathy Trial had more basal ganglia and thalamus lesions on brain magnetic resonance imaging but similar neurodevelopmental outcomes at 18 months of age than infants without perinatal sentinel events. Outcomes correlated with the neonatal magnetic resonance imaging findings.Trial registrationClinicalTrials.gov: NCT00005772.