In vitro investigation of electrophoretically deposited bioactive hydroxyapatite/chitosan coatings reinforced by graphene

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• 作者：Marija Đo&scaron ; ić^a ; Sanja Eraković^b ; Ana Janković^b ; Maja Vuka&scaron ; inović-Sekulić^b ; Ivana Z. Matić^c ; Jovica Stojanović^a ; Kyong Yop Rhee^d ; ^{rheeky@khu.ac.kr} ; ^{joveedu@naver.com} ; Vesna Mi&scaron ; ković-Stanković^b ; ^d ; ^{vesna@tmf.bg.ac.rs} ; Soo-Jin Park^e ; ^{sjpark@inha.ac.kr}
• 关键词：Coating materials ; Composite materials ; Electrochemical impedance spectroscopy ; X-ray diffraction ; Scanning electron microscopy
• 刊名：Journal of Industrial and Engineering Chemistry
• 出版年：2017
• 出版时间：25 March 2017
• 年：2017
• 卷：47
• 期：Complete
• 页码：336-347
• 全文大小：1915 K
• 卷排序：47

文摘

Graphene (Gr) and natural polymer chitosan (CS) were introduced to hydroxyapatite (HAP) to produce a three-component composite coating, which was fabricated by cathodic electrophoretic deposition on Ti substrates in an ethanol suspension. These HAP/CS/Gr coatings were characterized by X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FT-IR), thermogravimetric analysis (TGA), X-ray photoelectron spectroscopy (XPS) and electrochemical measurements and found that the graphene into HAP/CS composites significantly improves their morphology, thermal stability, and bioactivity. Both HAP/CS and HAP/CS/Gr composite coatings are classified as non-cytotoxic when tested against healthy peripheral blood mononuclear cells (PBMC), while antibacterial activity against Staphylococcus aureus and Escherichia coli could not be verified.