The stems of SCTZ's anti-diabetes effect and the fractions and constituents against the PTP1B and 伪-glucosidase mechanism is reported for the first time.
Four fractions and 10 known compounds were evaluated for protein tyrosine phosphatase 1B and 伪-glucosidase inhibitory activities from Schisandra chinensis (Turcz.) Baill.
All fractions and constituents exhibited significant inhibitory activities.
IC50 values of compound 1 and PE fraction for PTP1B was lower than 5 渭M or 渭g/mL.
IC50 values of EtOAc extract for 伪-glucosidase was lower than 2 渭g/mL.