Identification of a redox-modulatory interaction between selenoprotein W and 14-3-3 protein
详细信息 查看全文
- 作者：Yeong Ha Jeon ; Kwan Young Ko ; Jea Hwang Lee ; Ki Jun Park ; Jun Ki Jang ; Ick Young Kim ; ickkim@korea.ac.kr" class="auth_mail" title="E-mail the corresponding author
- 关键词：CDC25B ; cell division cycle 25 B ; DTT ; dithiothreitol ; EGFR ; epidermal growth factor receptor ; NMR ; nuclear magnetic resonance ; RICTOR ; rapamycin-insensitive companion of mTOR ; ROS ; reactive oxygen species ; Sec ; selenocysteine ; TAZ ; transcriptional co-activator with PDZ-binding motif
- 刊名：Biochimica et Biophysica Acta (BBA)-Molecular Cell Research
- 出版年：2016
- 出版时间：January 2016
- 年：2016
- 卷：1863
- 期：1
- 页码：10-18
- 全文大小：1384 K
文摘
- •
The interaction between SelW and 14-3-3 protein does not require phosphorylation.
- •
The selenocysteine of SelW is essential for interaction with 14-3-3 protein.
- •
Interaction of SelW with 14-3-3 protein is enhanced by oxidative stress.
- •
The mutant of SelW (U13S) does not rescue the effect of SelW depletion.