Quantitative risk assessment for skin sensitization: Success or failure?

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• 作者：Ian Kimber^a ; G. Frank Gerberick^b ; ^{gerberick.gf@pg.com} ; David A. Basketter^c
• 关键词：Skin sensitization ; Quantitative risk assessment ; Contact allergy
• 刊名：Regulatory Toxicology and Pharmacology
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：83
• 期：Complete
• 页码：104-108
• 全文大小：236 K
• 卷排序：83

文摘

The core toxicological principles of QRA include no effect level, safety factors, and human exposure. Effective monitoring by industry and dermatology community will help enable successful QRAs. If used properly, QRA for skin sensitization provides an effective tool for risk assessment.