Serum diamine oxidase activity is associated with lactose malabsorption phenotypic variation

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• 作者：Dietmar Enko^a ; ^b ; ^{dietmar.enko@gespag.at} ; Gernot Kriegshä ; user^a ; ^b ; ^{gernot.kriegshaeuser@gespag.at} ; Gabriele Halwachs-Baumann^a ; ^{gabriele.baumann@gespag.at} ; Harald Mangge^b ; ^{harald.mangge@medunigraz.at} ; Wolfgang J. Schnedl^c ; ^{w.schnedl@dr.schnedl.at}
• 关键词：LI ; lactose intolerance ; LM ; lactose malabsorption ; LHBT ; lactose hydrogen breath test ; LCT ; lactase gene ; DAO ; diamine oxidase ; HI ; histamine intolerance ; CO2 ; carbon dioxide ; H2 ; hydrogen
• 刊名：Clinical Biochemistry
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：50
• 期：1-2
• 页码：50-53
• 全文大小：323 K
• 卷排序：50

文摘

Lactose breath testing and serum diamine oxidase (DAO) measurements are performed. Association with lactose malabsorption phenotypic variation is investigated. Serum DAO activity level < 10 U/mL associates with higher exhaled H2 levels. Lactose malabsorbers with low DAO activity (< 10 U/mL) tend to report symptoms more often.