Structure stability of bovine submaxillary mucin (BSM) from 5 to 85 °C was studied.
BSM showed a structural loosening with heating, but it was reversible upon cooling.
Hydrodynamic size of BSM increased upon extended heating at 80 °C.
Adsorption of BSM onto hydrophobic surface decreased after heating at 80 °C.
Lubricity of BSM remained excellent even after extended heating at 80 °C.