The Spectrum and Regulatory Landscape of Intestinal Innate Lymphoid Cells Are Shaped by the Microbiome
详细信息 查看全文
- 作者：Meital Gury-BenAri1 ; 10 ; Christoph A. Thaiss1 ; 10 ; Nicolas Serafini2 ; 3 ; Deborah R. Winter1 ; Amir Giladi1 ; David Lara-Astiaso1 ; Maayan Levy1 ; Tomer Meir Salame4 ; Assaf Weiner1 ; Eyal David1 ; Hagit Shapiro1 ; Mally Dori-Bachash1 ; Meirav Pevsner-Fischer1 ; Erika Lorenzo-Vivas1 ; Hadas Keren-Shaul1 ; Franziska Paul1 ; Alon Harmelin5 ; Gé ; rard Eberl6 ; 7 ; Shalev Itzkovitz8 ; Amos Tanay9 ; James P. Di Santo2 ; 3 ; Eran Elinav1 ; eran.elinav@weizmann.ac.il" class="auth_mail" title="E-mail the corresponding author ; Ido Amit1 ; 11 ; ido.amit@weizmann.ac.il" class="auth_mail" title="E-mail the corresponding author
- 关键词：innate lymphoid cells ; epigenome ; single-cell transcriptomics ; microbiota
- 刊名：Cell
- 出版年：2016
- 出版时间：25 August 2016
- 年：2016
- 卷：166
- 期：5
- 页码：1231-1246.e13
- 全文大小：10957 K
文摘
- •
Transcriptional and chromatin landscapes of innate lymphoid cells
- •
Functional compartmentalization within ILC subsets revealed by single-cell RNA-seq
- •
Impact of commensal microbiota on epigenetic regulation and gene expression of ILCs
- •
Single-cell analysis of whole-transcriptome responses to microbial colonization