Unsaturated Lipid Assimilation by Mycobacteria Requires Auxiliary cis-trans Enoyl CoA Isomerase
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- 作者：Sonali Srivastava1 ; 2 ; Sarika Chaudhary1 ; Lipi Thukral1 ; Ce Shi3 ; Rinkoo D. Gupta1 ; Radhika Gupta1 ; 2 ; K. Priyadarshan4 ; Archana Vats1 ; Asfarul S. Haque4 ; Rajan Sankaranarayanan4 ; Vivek T. Natarajan1 ; 2 ; Rakesh Sharma1 ; Courtney C. Aldrich3 ; Rajesh S. Gokhale1 ; 2 ; 5 ; rsg@igib.res.in" class="auth_mail" title="E-mail the corresponding author
- 刊名：Chemistry & Biology
- 出版年：2015
- 出版时间：17 December 2015
- 年：2015
- 卷：22
- 期：12
- 页码：1577-1587
- 全文大小：2829 K
文摘
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Mtb fatty acid degradation complex cannot degrade cis-unsaturated fatty acid
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Stand-alone Ech protein complements Mtb FadAB in oleic acid degradation
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F287 constrains binding of kinked cis substrate in Mtb FadB active site
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Mtb Ech proteins can be classified as monofunctional or bifunctional enzymes