MART-10, the vitamin D analog, is a potent drug to inhibit anaplastic thyroid cancer cell metastatic potential
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- 作者：Kun-Chun Chianga ; b ; 1 ; Sheng-Fong Kuob ; c ; 1 ; Chih-Hung Chenb ; c ; Sohching Ngb ; c ; Shu-Fu Lind ; Chun-Nan Yeha ; Li-Wei Chene ; Masashi Takanof ; Tai C. Cheng ; Horng-Heng Juangh ; Atsushi Kittakaf ; akittaka@pharm.teikyo-u.ac.jp" class="auth_mail" title="E-mail the corresponding author ; Jen-Der Lind ; einjd@adm.cgmh.org.tw" class="auth_mail" title="E-mail the corresponding author ; Jong-Hwei S. Pangi ; jonghwei@mail.cgu.edu.tw" class="auth_mail" title="E-mail the corresponding author
- 关键词：Anaplastic thyroid cancer ; Vitamin D ; MART-10 ; Migration ; Invasion ; EMT
- 刊名：Cancer Letters
- 出版年：2015
- 出版时间：1 December 2015
- 年：2015
- 卷：369
- 期：1
- 页码：76-85
- 全文大小：2389 K
文摘
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Anaplastic thyroid cancer is a very aggressive disease without effective treatment available.
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MART-10 MART-10 has been shown to be more pottent than 1α,25(OH)2D3 in inhibitin a variety of cancers growth.
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MART-10 and 1α,25(OH)2D3 both are effitve drug to inhibt anaplastic thyroid cancer metasasis with MART-10 much more poten, encouraging further in vivo studies.
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