Diagnostic usefulness of dynamic changes of CMV-specific T-cell responses in predicting CMV infections in HCT recipients

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• 作者：Jiwon Jung^a ; ^d ; Hyun-Jung Lee^a ; Sun-Mi Kim^a ; Young-Ah Kang^b ; Young-Shin Lee^b ; Yong Pil Chong^a ; Heungsup Sung^c ; Sang-Oh Lee^a ; Sang-Ho Choi^a ; Yang Soo Kim^a ; Jun Hee Woo^a ; Jung-Hee Lee^b ; Je-Hwan Lee^b ; Kyoo-Hyung Lee^b ; Sung-Han Kim^a ; ^{kimsunghanmd@hotmail.com}
• 关键词：Cytomegalovirus ; Hematopoietic stem cell transplantation ; ELISPOT
• 刊名：Journal of Clinical Virology
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：87
• 期：Complete
• 页码：5-11
• 全文大小：1203 K
• 卷排序：87

文摘

High CMV-specific T cell response at day 0 in hematopoietic stem cell transplant (HCT) recipients was associated with CMV infection after HCT. Low CMV-specific T cell response at day 30 in HCT recipients was associated with CMV infection after HCT. Monitoring dynamic changes of CMV-specific immunity is useful for identifying HCT recipients at risk of CMV infection.