Combining transbronchial biopsy using endobronchial ultrasonography with a guide sheath and positron emission tomography for the diagnosis of small peripheral pulmonary lesions

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• 作者：Hidenori Mizugaki ; Naofumi Shinagawa ; Kakuko Kanegae ; Noriyuki Yamada ; Hajime Asahina ; Eiki Kikuchi ; Satoshi Oizumi ; Nagara Tamaki ; Masaharu Nishimura
• 关键词：Peripheral pulmonary lesions ; Endobronchial ultrasonography with a guide sheath ; Transbronchial biopsy ; Positron emission tomography with fluorodeoxyglucose ; Standardized uptake value
• 刊名：Lung Cancer
• 出版年：2010
• 出版时间：May 2010
• 年：2010
• 卷：68
• 期：2
• 页码：211-215
• 全文大小：388 K

文摘

To evaluate the combination of transbronchial biopsy (TBB) using endobronchial ultrasonography with a guide sheath (EBUS-GS) and positron emission tomography with fluorodeoxyglucose (FDG-PET) for the diagnosis of small peripheral pulmonary lesions (PPLs) ≤30 mm in mean diameter. A total of 74 PPLs (69.2 % ) were diagnosed by TBB using EBUS-GS with X-ray fluoroscopy. Diagnostic yield by FDG-PET was 78.5 % for the 107 PPLs examined. Diagnostic yield with the combination of TBB using EBUS-GS and FDG-PET (90.7 % ) was significantly higher compared with that for each procedure alone. A significant increment in diagnostic yield with this combination was seen for PPLs >20 mm and ≤30 mm and for malignant lesions. Combination of TBB using EBUS-GS and FDG-PET is useful for the diagnosis of small PPLs.