Effects of a Bioactive Scaffold Containing a Sustained Transforming Growth Factor-β1-releasing Nanoparticle System on the Migration and Differentiation of Stem Cells from the Apical Papilla
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- 作者：Craig Bellamy ; DDS ; Suja Shrestha ; MSc ; PhD ; Calvin Torneck ; DDS ; MS ; Anil Kishen ; BDS ; MDS ; PhD ; akishen@gmail.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：Cell migration ; chitosan nanoparticles ; odontogenic differentiation ; regenerative endodontic procedures ; stem cells from apical papilla ; transforming growth factor-β1
- 刊名：Journal of Endodontics
- 出版年：2016
- 出版时间：September 2016
- 年：2016
- 卷：42
- 期：9
- 页码：1385-1392
- 全文大小：1656 K
文摘
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Demonstrates the potential of chitosan scaffold with TGF-β1–releasing nanoparticles on SCAP.
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The engineered scaffold/nanoparticle significantly enhanced SCAP migration and differentiation.
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The results of this study may have direct application to improve current endodontic regenerative protocols.