Salinomycin suppresses TGF-β1-induced epithelial-to-mesenchymal transition in MCF-7 human breast cancer cells
详细信息 查看全文
- 作者：Chunying Zhanga ; Ying Lua ; Qing Lia ; Jun Maob ; Zhenhuan Houa ; Xiaotang Yua ; Shujun Fana ; Jiazhi Lia ; Tong Gaoa ; Bing Yana ; Bo Wanga ; Bo Songa ; Lianhong Lia ; b ; lilianhong9177@163.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：Epithelial-to-mesenchymal transition ; Breast cancer MCF-7 cells ; Salinomycin ; TGF-β/Smad signaling ; TGF-β/Non-Smad signaling
- 刊名：Chemico-Biological Interactions
- 出版年：2016
- 出版时间：25 March 2016
- 年：2016
- 卷：248
- 期：Complete
- 页码：74-81
- 全文大小：1865 K
文摘
- •
Sal inhibits TGF-β1-induced invasion and migration.
- •
Sal inhibits TGF-β1-induced EMT.
- •
Sal inhibits TGF-β1-induced activation of Smad signaling.
- •
Sal inhibits TGF-β1-induced activation of non-Smad signaling.
- •
Correlation among E-cadherin, β-catenin, and metastatic potential of breast cancer.