Regulation of cyclooxygenase-2 expression in rat oviductal epithelial cells: Evidence for involvement of GPR30/Src kinase-mediated EGFR signaling
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- 作者：Pooja Popli ; Vijay Kumar Sirohi ; Murli Manohar ; Vinay Shukla ; Jyoti Bala Kaushal ; Kanchan Gupta ; Anila Dwivedi ; anila.dwivedi@rediffmail.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：Oviductal epithelial cells ; COX-2 ; GPR30 ; Src kinase ; EGFR
- 刊名：Journal of Steroid Biochemistry and Molecular Biology
- 出版年：2015
- 出版时间：November 2015
- 年：2015
- 卷：154
- 期：Complete
- 页码：130-141
- 全文大小：2219 K
文摘
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Estrogen regulates COX-2 expression in via GPR30 in rat oviductal epithelial cells.
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Estrogen-mediated COX-2 expression is regulated by both EGFR and PI3K signalling.
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GPR30/Src kinase-mediated EGFR signaling is involved in regulation of COX-2.