Synthesis, characterization and biological activities of some Ru(II) complexes with substituted chalcones and their applications as chemotherapeutics against breast cancer
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- 作者：Ashok K. Singha ; singhaks3@rediffmail.com" class="auth_mail" title="E-mail the corresponding author ; Gunjan Saxenaa ; Shivani Dixitb ; Hamidullahb ; Sachin K. Singhc ; Sudheer K. Singhc ; M. Arshadd ; Rituraj Konwarb ; r_konwar@cdri.res.in" class="auth_mail" title="E-mail the corresponding author
- 关键词：Ru(II)-DMSO complexes ; Breast cancer ; DNA topoisomerase ; Circular dichroism ; DNA binding
- 刊名：Journal of Molecular Structure
- 出版年：2016
- 出版时间：5 May 2016
- 年：2016
- 卷：1111
- 期：Complete
- 页码：90-99
- 全文大小：1949 K
文摘
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Four new Ru(II)DMSO chalcone complexes were synthesized.
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Complexes were investigated via multi-technique experimental approach.
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Complexes and ligands were screened for anti-breast cancer activities.
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