Oxidative stress induces the decline of brain EPO expression in aging rats
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- 作者：Xu Lia ; b ; c ; Yubao Chena ; b ; c ; Siying Shaoa ; b ; c ; Qing Tanga ; b ; c ; Weihai Chend ; Yi Chena ; b ; c ; Xiaoyu Xua ; b ; c ; xuxiaoyu@swu.edu.cn" class="auth_mail" title="E-mail the corresponding author
- 关键词：Aging ; EPO ; Brain ; Oxidative stress ; HIF-2α
- 刊名：Experimental Gerontology
- 出版年：2016
- 出版时间：October 2016
- 年：2016
- 卷：83
- 期：Complete
- 页码：89-93
- 全文大小：779 K
文摘
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Brain EPO expression was decreased in d-gal-induced aging model.
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The decline of EPO was correlated with oxidative stress.
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HIF-2a was involved in Oxidative stress inducing the decline of EPO.