Role of the suppressor of cytokine signaling 2 (SOCS2) during meningoencephalitis caused by Bovine herpesvirus 5 (BoHV-5)
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- 作者：Aline Aparecida Silva Barbosab ; 1 ; alinesb.bio@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Alice Freitas Versianib ; 1 ; alicefv_vet@yahoo.com.br" class="auth_mail" title="E-mail the corresponding author ; Larissa Fonseca da Cunha Sousad ; laris.fonseca@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Aline Silva de Mirandac ; mirandas.aline@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Marcela Ribeiro Gasparinib ; marcela.gasparini@pirbright.ac.uk" class="auth_mail" title="E-mail the corresponding author ; Fá ; tima Brantd ; fatimacbrant@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Daniele Gonç ; alves Silvaa ; danivets@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Iracema Luisa Quintino-de-Carvalhob ; iracemaluisa@yahoo.com.br" class="auth_mail" title="E-mail the corresponding author ; Frederico Marianetti Sorianie ; fredsori@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Flá ; vio Guimarã ; es da Fonsecab ; fdafonseca@cpqrr.fiocruz.br" class="auth_mail" title="E-mail the corresponding author ; Anilton Cé ; sar Vasconcelosa ; anilton@icb.ufmg.br" class="auth_mail" title="E-mail the corresponding author ; Lucí ; ola da Silva Barcelosf ; aloicul@yahoo.com" class="auth_mail" title="E-mail the corresponding author ; Mauro Martins Teixeirad ; mmtex.ufmg@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Antô ; nio Lú ; cio Teixeirag ; altexr@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Fabiana Simã ; o Machadod ; machadofs@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Edel Figueiredo Barbosa-Stanciolib ; edelfb@icb.ufmg.br" class="auth_mail" title="E-mail the corresponding author ; Milene Alvarenga Rachida ; milenerachid@gmail.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：Bovine herpesvirus 5 ; Brain ; Inflammation ; SOCS2 ; Mice
- 刊名：Comparative Immunology, Microbiology and Infectious Diseases
- 出版年：2016
- 出版时间：August 2016
- 年：2016
- 卷：47
- 期：Complete
- 页码：26-31
- 全文大小：787 K
文摘
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SOCS2 plays a role in the pathogenesis of experimental BoHV-5 meningoencephalitis.
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SOCS2 deficient mice infected with BoHV-5 exhibited enhancement of neuropathology and brain inflammatory parameters associated with widespread distribution of the virus.
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SOCS2 participates in the control of interferon IFNα/β system against BoHV-5 infection.
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