A physical model for dementia

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• 作者：O. Sotolongo-Costa^a ; ^{osotolongo@uaem.mx} ; L.M. Gaggero-Sager^b ; ^{lgaggero@uaem.mx} ; J.T. Becker^c ; ^d ; ^e ; ^{BeckerJT@upmc.edu} ; F. Maestu^f ; ^{fernando.maestu@ctb.upm.es} ; O. Sotolongo-Grau^g ; ^{osotolongo@fundacioace.com} ; for the Alzheimer&rsquo ; s Disease Neuroimaging Initiative¹
• 关键词：Dementia ; Cusp ; Catastrophe theory ; Stochastic process
• 刊名：Physica A: Statistical Mechanics and its Applications
• 出版年：2017
• 出版时间：15 April 2017
• 年：2017
• 卷：472
• 期：Complete
• 页码：86-93
• 全文大小：507 K
• 卷排序：472

文摘

A thermodynamical model for relating brain networks with energy is proposed. A Langevin equation is obtained and its Fokker–Planck equation is solved. The model is successfully compared with the known experimental data. The cusp model used gives a new probabilistic interpretation to the dementia onset. Results support known facts of dementia and shed light on issues of related diseases.